CYTOLOGICAL RESPONSES OF BROWN FAT TISSUE IN COLD-EXPOSED RATS
نویسندگان
چکیده
منابع مشابه
Cytological Responses of Brown Fat Tissue in Cold-exposed Rats
In young adult laboratory rats exposed to cold (6 degrees C) the brown adipose tissue undergoes time-dependent increases in cellularity, vascular supply, and total mass. These changes are largely complete after 16 days in the cold and concurrent generally with the development of a thermoregulatory state not greatly dependent upon shivering. Histologically the brown fat changes from a tissue hav...
متن کاملUltrastructural and Biochemical Changes in Brown Fat in Cold-exposed Rats
During the first 3 days of exposure of rats to 5 degrees C, the nitrogen concentration of interscapular brown fat increased by 50% and remained at this elevated level for the duration of the 8-wk observation period, while the mass of tissue increased fourfold. The concentration of both DNA and RNA per unit nitrogen reached a maximum after 3 days, then declined; however, the total quantity of ea...
متن کاملCellular proliferation and UCP content in brown adipose tissue of cold-exposed aging Fischer 344 rats.
Previous investigations have demonstrated that older vs. younger rats respond to cold exposure with blunted cold-induced nonshivering thermogenesis of brown adipose tissue (BAT). This reduction in nonshivering thermogenesis is associated with reduced mass and blunted nonshivering thermogenic capacity of BAT. The purpose of this study was to test the hypothesis that brown fat in 26-mo-old Fische...
متن کاملNorepinephrine release in brown adipose tissue remains robust in cold-exposed senescent Fischer 344 rats.
Near the end of life, old F344 rats undergo a transition, marked by spontaneous and rapidly declining function. Food intake and body weight decrease, and these rats, which we call senescent, develop severe hypothermia in the cold due in part to blunted brown fat [brown adipose tissue (BAT)] thermogenesis. We tested the hypothesis that this attenuation may involve diminished sympathetic signalin...
متن کاملMuscle and brown adipose tissue fatty acid profiles in cold-exposed rats.
Effects of cold acclimation and cold exposure for 25 generations on triglyceride (TG)-, total phospholipid (PL)-, and cardiolipin (CL)-fatty acid (FA) compositions were studied in the different types of skeletal muscles (red and white muscles from quadriceps, and soleus) as well as brown adipose tissue (BAT) in rats. TG: in cold-acclimated rats (CA) and rats reared in cold for 25 generations (2...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1964
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.23.1.89